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Hirata et al (126) developed hybrid molecules that combine the oxidized indole structure of neuroprotective agents with the polyphenolic structure of curcumin, applying them to mouse hippocampal HT22 cells

The evidence base combines animal models showing dramatic retinal preservation, early-stage human trials demonstrating measurable improvements in visual function tests, and mechanistic studies explaining how specific peptides interact with retinal cells and vascular structures

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Data are presented as the mean standard deviation(SD) for independent experiments