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In the first enzyme reaction, methylcobalamin is used to recycle the folate cofactor 5-methyltetrahydrofolate to tetrahydrofolate thereby allowing the folate cofactor to participate in a cycle involving the biosynthesis of purines and pyrimidines

It is a dual incretin therapy that activates both GLP-1 and GIP receptors, pathways known to regulate glucose metabolism, appetite, and energy balance

An important antioxidant, glutathione, or GSH, cannot be used as a supplement because this substance cannot directly enter the cells threatened by oxidative stress

[DOI] [PubMed] [Google Scholar] 141.Shahripour R.B., Harrigan M.R., Alexandrov A.V