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doi:10.1016/j.bcp.2004.07.023

Research in specific autoimmune diseases A study published in the journal Annals of the New York Academy of Sciences examined serum thymosin alpha-1 levels in patients with autoimmune diseases including psoriatic arthritis, rheumatoid arthritis , and systemic lupus erythematosus

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This distinction has real biological consequences: a localized, self-limiting signal and a persistent, body-wide one are not merely different doses of the same thing, and the animal literature on localized IGF-1 expression illustrates why