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GLP-1R agonists also demonstrate neuroprotective effects, including reduction of neuroinflammation, oxidative stress, and neuronal apoptosis, with emerging evidence for benefit in neurodegenerative diseases such as Parkinsons and Alzheimers disease [75, 76]

Based on their absence of a fluorescent marker, their robust ATP-responsiveness (mean SEM 340/380 ratio = 4.7 0.3, n = 26), and their multipolar morphology, these are likely satellite-glial cells (SGCs) arising from the nodose ganglion (Supplementary Figure 4)

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