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"These drugs could transform weight-loss treatment, offering hope to millions of people struggling with obesity, a major risk factor for life-threatening conditions like diabetes and heart disease," said first author Areesha Moiz, a master's graduate of McGills Division of Experimental Medicine

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Noteworthy, new serious adverse event (AE) signals were identified, including hemorrhagic diarrhea (ROR: 3.69), hepatic pain (ROR: 4.20), abnormal hormone levels (ROR: 6.51), and pancreatic failure (ROR: 36.34) in subcutaneous semaglutide, and Dupuytrens contracture (ROR: 46.85) in oral semaglutide