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Incretins are gut-derived peptide hormones, primarily GLP-1 and GIP, secreted after nutrient intake to enhance glucose-dependent insulin release from pancreatic cells

Thereby inhibiting cancer cell proliferation, promoting apoptosis, and suppressing tumor angiogenesis and metastasis.In addition, the product can be used to explore the association between NNMT and inflammatory response, thus clarifying its indirect role in cancer development

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The difference observed in the blood GLP-1 responses from glucose, insulin and GIP may have been due to the direct stimulatory effects of coffee polyphenols on the release of GLP-1