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Opened vials: yes, refrigerate at 2-8C
Variants in genes affecting androgens, inflammation, and nutrient metabolism (such as those in the iron-transport and follicle-cycling pathways) determine whether a patient will develop clinically significant telogen effluvium during weight loss
Future studies are needed, particularly in clearly defined organ-involved settings such as lupus nephritis, to combine single-cell analysis, spatial transcriptomics, and metabolic flux analysis in order to distinguish the pathogenic driving role of metabolic alterations from their role as accompanying biomarkers
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