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A new study published in ACR Open Rheumatology Journal looked at patients with RA who began treatment with a GLP-1 agonist, either semaglutide or tirzepatide, for obesity

Adverse Reactions/Side Effects The following serious adverse reactions are described below or elsewhere in the prescribing information: Risk of Thyroid C-Cell Tumors [see Warnings and Precautions (5.1)] Acute Pancreatitis [see Warnings and Precautions (5.2)] Acute Gallbladder Disease [see Warnings and Precautions (5.3)] Risk for Hypoglycemia with Concomitant Use of Anti-Diabetic Therapy [see Warnings and Precautions (5.4)] Heart Rate Increase [see Warnings and Precautions (5.5)] Acute Kidney Injury Due to Volume Depletion [see Warnings and Precautions (5.6)] Severe Gastrointestinal Adverse Reactions [see Warnings and Precautions (5.7)] Hypersensitivity Reactions [see Warnings and Precautions (5.8)] Pulmonary Aspiration During General Anesthesia or Deep Sedation [see Warnings and Precautions (5.9)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice

doi: 10.3390/coatings11050501 139 WangKYangXWuZWangHLiQMeiHet al

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