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Tirzepatide, the first single-molecule, dual GIP and GLP-1 receptor agonist, is licensed in the UK for the treatment of both type 2 diabetes and obesity, and has been demonstrated to slow gastric emptying, increase insulin sensitivity and glucose-dependent insulin secretion, and decrease glucagon secretion and appetite

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And, for what its worth, there is some data to suggest yerba mate may be associated with losing weight: It stimulates lipolysis, the breakdown of fats, according to 2019 research in the Brazilian Journal of Pharmaceutical Sciences

PMID: 30646146, PMCID: PMC6324513, DOI: 10.1001/jamanetworkopen.2018.2044