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15 Thus, as demonstrated in the current case, early detection of neurologic deficits is critical because they may be at least partially vitamin B 12 supplementation can at least partially reverse neurologic deficits

In hepatocellular carcinoma, PRMT1 catalyzes the methylation of PHGDH at residue R236 to enhance its enzymatic activity ( The tumor classification based on SSP activation patterns reveals that the conserved mechanisms of SSP, including redox homeostasis maintenance, one-carbon metabolism and drug resistance regulation, can serve as universal targets for pan-cancer therapeutic interventions

When the body's tissues become less responsive to insulin, a condition known as insulin resistance, it increases the risk of type 2 diabetes mellitus (T2DM), metabolic syndrome, fatty liver disease, and atherosclerosis (Lee et al., 2022)