Acknowledgements This work was supported in part by grants from Fondo de Investigacin Sanitaria (www.isciii.es) (PI15/ 00713) and GEHEP-SEIMC (GEHEP-004)
GLP-1 Drugs GLP-1 drugs provide multiple options for Type 2 diabetes treatment: Reduce HbA1c by 1-2% when used properly Tirzepatide shows superior blood sugar control compared to semaglutide Compounded semaglutide offers the same diabetes benefits as brand-name versions Ozempic Ozempic specifically targets Type 2 diabetes with proven results: FDA-approved specifically for diabetes management One trial found "the rate of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke was significantly lower among patients receiving semaglutide" Helps patients with chronic kidney disease too Dosage and Administration Both types are usually weekly injections, but dosing steps differ
Testosterone therapy, long used in men to build muscle, is increasingly recognized as an option for some women
Going back to the IEL cells for a moment, in Crohns disease and ulcerative colitis (UC) these cells can start to attack the gut lining itself, this further creates a cytotoxic environment, which can further exacerbate IELs to produce pro-inflammatory proteins, this can lead to a compromised intestinal lining, along with alterations in the gut microbiome
