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Other, more sudden changes in vision, like eye strokes and NAION, can lead to blindness, particularly in one eye

While genetic variations in GLP-1 receptor expression or downstream signaling pathways may influence individual treatment response, routine genetic testing isn't currently recommended for predicting outcomes

In this process, alcohol directly leads to the overgrowth and enrichment of some gut microbiota, such as Actinobacteria , Proteobacteria , Enterobacteriaceae , Corynebacterium and Streptococcus , while the abundance of other gut microbiota subsequently decreases, such as Bacteroidetes and Akkermansia genera of the phyla Verrucomicrobia , Lactobacillus , Ruminococcus , Faecalibacterium and Roseburia of the phylum Firmicutes ( Lactobacilli leads to a reduction in the synthesis of saturated long-chain fatty acids, which in turn accelerates hepatic lipid metabolism, oxidative stress, inflammation and fibrosis, thereby attenuating its protective effect on the liver ( Figure 2 During ALD treatment, strategies to modulate gut microbiota are gradually being recognized, which is closely related to the nonnegligible effects of TCMs and NPs ( Table 1 )

Rare but more serious side effects can include pancreatitis or gallbladder disease