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Wegovy is an FDA-approved once-weekly injection for chronic weight management in adults with obesity, or overweight with a related health condition
Notably, within the second-line diabetes medication group, 283,321 had a DPP-4i prescription, 321,508 had a SGLT2i prescription and 484,113 had a sulfonylurea prescription
Staying at a sub-therapeutic dose indefinitely is a common reason for treatment failure
A landmark 2022 cardiovascular trial showed that GLP-1 receptor agonists like semaglutide result in 1015% body weight reduction, while metformin typically produces only 23% weight loss
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