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Here is a list of some of the approved clinical trial sites in Singapore for medical devices: **ASTAR Clinical Research Centre (ACRC) National University of Singapore (NUS) Yong Loo Lin School of Medicine Singapore General Hospital (SGH) National Heart Centre Singapore (NHCS) Tan Tock Seng Hospital (TTSH) Changi General Hospital (CGH) KK Womens and Childrens Hospital (KKH) National Neuroscience Institute (NNI) Singapore Eye Research Institute (SERI) To be approved as a clinical trial site, the site must meet certain requirements, such as having qualified personnel and having the necessary facilities

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Of note, even before the introduction of the newer classes of medications, multifactorial, target-driven therapies addressing glycaemic, blood pressure and lipid control that incorporated reninangiotensin system blockade, the use of statins and attention to lifestyle factors significantly reduced the progression to end-stage kidney disease by about 50% in people with type 2 diabetes, hypertension and microalbuminuria