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Heterogeneity of endometriosis lesions requires individualisation of diagnosis and treatment and a different approach to research and evidence based medicine
300 In the parental ID8 murine ovarian cancer model harbouring a knock-out of p53 (ID8p53) and MISIIR-Tag spontaneous ovarian cancer models, CGX-1321(Wnt inhibitor) increased infiltrating CD8 + T cells in the TME and decreased tumour burden
Additionally, research indicates upregulation of growth hormone receptor expression in tendon-derived fibroblasts, potentially amplifying growth hormonemediated proliferative responses during repair
