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The other differentiating factor is weight loss, as people with type 2 diabetes tend to gain weight and GLP-1 products promote weight loss
The major brain region for the synthesis of dopamine is the substantia nigra which is located below the posterior hypothalamus and next to the ventral tegmental area
N Engl J Med 387 , 205216 (2022)
With insulin, there is risk of weight gain, for hypoglycemia, and theres more treatment burden and need for glucose monitoring. GLP-1 drugs have also been shown to have cardiovascular benefits, she adds, though further clinical trials are needed to assess orforgliprons effects on heart health
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