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The aim of this narrative review is to provide a broad overview on the pharmacologic aspects of glutathione, with a focus on current clinical data on its use for metabolic liver disease

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Senescent erythrocytes are characterized by loss of surface area and volume [66], increased cell density [67], reduced deformability [68], cation loss [69], membrane desialylation [70], enzymatic dysregulation [69], oxidative stress [71], hemichrome abundance [69], elevated levels of glycated hemoglobin [72], reduced expression of phagocytosis-inhibiting CD47 [73], altered protein 4.1a/protein 4.1b ratio [74], etc

Tubular injury triggers podocyte dysfunction by -catenindriven release of MMP-7