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The goal is to find the minimum effective dose

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Reduced arsenic accumulation in rice ( Oryza sativa L.) shoot involves sulfur mediated improved thiol metabolism, antioxidant system and altered arsenic transporters

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When vitamin B12 is supplemented and the skin appearance deteriorates, the folic acid and biotin status in the blood should also be measured

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Additionally, cytosolic LPS is directly sensed by inflammatory caspases (e.g., Caspase-4), triggering non-canonical inflammasome responses and pyroptosis, which further amplifies systemic inflammation 144

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