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150 A randomized, double-blind, placebo-controlled trial in 84 women with PCOS found that 6 mg of melatonin, along with 250 mg magnesium oxide, daily for eight weeks reduced unwanted hair growth, serum insulin, total testosterone, total and LDL-cholesterol, and raised HDL-cholesterol and total antioxidant capacity compared with baseline

Symptoms include localised injection site redness and swelling, or systemic signs such as widespread hives, facial swelling, breathing difficulty, or cardiovascular collapse