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Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination

There are several potential targets for pharmacological intervention aimed at modifying Parkinson's disease, including addressing neuroinflammation, mitochondrial dysfunction, oxidative stress, calcium channel activity, LRRK2 kinase activity, -synuclein accumulation, aggregation, and cell-to-cell transmission

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These risk differences (drug-placebo difference in the number of cases of suicidality per 1000 patients treated) are provided in Table 1