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Pathogenic variants in the LYST gene underlie this syndrome, which is often fatal in the first decade of life.[123-125] Griscelli syndrome, also inherited in an autosomal recessive manner, was originally described as decreased cutaneous pigmentation with hypomelanosis and neurologic deficits, but its clinical presentation is quite variable

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4 End-of-treatment response is an undetectable HCV RNA test at the end of treatment week 24 or 48

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Rudke, A

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