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Case size: 90x50x26 mm

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The low median age at death of this sample lends support to previous findings that socio-economically disadvantaged populations have lower life expectancies than the general population

The main pharmacokinetic indices altered in smokers compared to non-smokers indicated that the effective concentration of the drug at plasma level was achieved lower in smokers than in non-smokers at the same dose administered and, in general, a reduction in the bodys exposure to the drug