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Additional information Edited by A Stephanou Supplementary Information accompanies the paper on Cell Death and Disease website Supplementary information Rights and permissions This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported License

COPD prevalence was not found to be lower in exclusive e-cigarette users compared to exclusive cigarette smokers, and when compared to never tobacco use, current e-cigarette use and cigarette and e-cigarette dual use were associated with increased COPD prevalence