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The finish is smooth and lingering, evoking the experience of pairing a quality cigar with a hot latte or cappuccino

Sample size An initial sample size calculation used the estimate of the within-arm SD of cigarettes per day from a pilot study (5.1 (95% CI [3.7, 8.2]: Additional File 1), which indicated that a sample size of 206 participants would give 80% power at the 5% significance level and a two-sided test to detect a difference of two cigarettes per day

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in those analyses, semaglutide-treated participants showed larger reductions in laboratory cigarette consumption following treatment