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For instance, if you burn a whole box of incense in one day, youre exposing yourself to an excessive amount of smoke
Smoking causes lung cancer, which is also the most common cause of cancer death
In any other industry they would be shown the door by their board and shareholders
Beyond Parkin, additional E3 ubiquitin ligases such as SMAD-specific E3 ubiquitin protein ligase 1 (SMURF1), glycoprotein 78 (Gp78), mitochondrial ubiquitin ligase 1 (MUL1), seven in absentia homolog 1 (SIAH1), and Ariadne RBR E3 ubiquitin protein ligase 1 (ARIH1) also contribute to mitophagy regulation through ubiquitination of mitochondrial proteins [83]
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