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The book received considerable attention, including a favorable review in The New York Times Book Review on July 14, 1957.) In the ARGOSY article, Northrup argues that air pollution and constitutional factors are the likely causes of lung cancer and downplays the growing evidence of smoking as a cause of cancer by pointing out that the studies were all done on mice, guinea pigs, and machines

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They also contain nicotine and often include fillers, sweeteners, and flavors