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Arthur Conan Doyles protagonist, Holmes, regularly indulges in intelligent monologues fuelled by his nicotine addiction, and often solves his cases either whilst smoking (in The Man with the Twisted Lip, for example) or by observing tobacco-related clues, such as tobacco ash
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1 Among 22 studies which met inclusion criteria, these studies described 40 different parent compounds and four metals found in the urine of e-cigarette users
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