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Story highlights In the United States and Europe, cigarette smoking initiation peaks around 15 years old Cigarettes are on the decline, but e-cigarettes are on the rise among US kids Cigarette smoking may be declining worldwide, but tobacco use is still responsible for the deaths of about 6 million people globally each year, according to the World Health Organization

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The reduced digestive impact of NRTs likely results from: Lower peak nicotine levels compared to cigarettes or snus More gradual nicotine absorption rates Absence of additional tobacco compounds that may affect digestion Steady release formulations (especially patches) that prevent nicotine spikes For people quitting smoking who are concerned about constipation, transitioning through nicotine pouches or gum before eliminating nicotine completely might help manage digestive changes more comfortably