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Presence of the T allele (either T/T or A/T genotype) is associated with a higher risk of serious hypersensitivity reactions, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), maculopapular eruptions, and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), when taking certain mood stabilizers, specifically carbamazepine

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