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Cell 126:349359 Yamada Y, Tomaru U, Ishizu A, Ito T, Kiuchi T, Ono A, Miyajima S, Nagai K, Higashi T, Matsuno Y, Dosaka-Akita H, Nishimura M, Miwa S, Kasahara M (2015) Decreased proteasomal function accelerates cigarette smoke-induced pulmonary emphysema in mice

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The extraoral examination should begin with an examination of the skin of the face and in particular the perioral region, palpation of the submandibular and submental lymph nodes, and palpation of the temporomandibular joints for clicking or pain on opening