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There are more than 7,000 chemical components found in cigarette smoke and hundreds of them are harmful to human health, according to the Centers for Disease Control and Prevention

There also appears to be a genetic element to all this variations in the CNR1 gene (which encodes for the expression of CB-receptors) are associated with variations in susceptibility to nicotine dependence

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The reason, stepping back, people are using these pouches is because they get nicotine from them, Deputy Solicitor General William Cole said during oral arguments