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In addition, BHB inhibits NLRP3 activation, resulting in a reduced release of inflammatory factors, particularly IL-1 and IL-18, by inhibiting caspase-1 activation (176, 190)

American Cancer Society, Atlanta, GA, pp 2932 Acknowledgements The authors research on cigarette smoking and cancer is supported by grants CA-81301, CA-92025, CA-102502, DA-13333, and ES-11297 from the U.S