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Manufacturers must complete a comprehensive approval process to register an NRT with the FDA

The estimated number of deaths from smoking-related causes rose from 500,000 in 1996 to 700,000 in 2002 to around 1.2 million in 2009 and is expected to rise to 2 million in 2025

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Familiarity: They provide a taste similar to traditional cigarettes, making them appealing for former smokers