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[18] For example, a study evaluating the impacts of restrictions on the sale of flavored tobacco products found that in cities with restrictions on the sale of flavored tobacco products, exterior store advertising for tobacco products overall decreased following implementation of the policies to a greater extent than cities without a restriction in place

And after that, your liver goes into overdrive just trying to deal with the alcohol

Extracellular matrix breakdown products from injured or inflamed tissues have also been identified as potent endogenous danger signals

It is often performed in an inpatient setting where alcohol is not available