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According to the literature, current smokers whether they smoked conventional cigarettes or use other forms of tobacco were at increased risk for olfactory and gustatory dysfunction

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The PMTA assessment process needs non-marginal re-engineering so that at least 4,000 ENDS products can be authorized (to compete against as many as 100,000 illicit products), that barriers to entry and application costs need to fall by a factor of at least ten (in line with the 2016 Deeming Rule Impact Analysis), and so that applications can be processed within 180 days (in line with the law)