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Regarding the long-term effects of e-cigarette smoking on cardiac autonomic tone, a cross-sectional study comparing cases (e-cigarette users) and controls (healthy individuals with no history of smoking) who had used nicotine-containing e-cigarettes on most days for at least 1 year, showed a significant increase in sympathetic activity compared to the control group (30)
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The consumption of smokeless tobacco is higher due to the greater social acceptance, curiosity, and culture, which are influencing factors for SLT initiation and prevalence
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