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Controlled variables The selection of control variables was informed by a review of the extant literature on adolescent health and sleep 3 , as well as biological plausibility regarding potential confounding factors

An equally important limitation is the fact that most of the data were collected while cannabis was illegal in Massachusetts, so it is difficult to know to what extent men may have under-reported use of cannabis because of social stigma or potential consequences related to insurance coverage for infertility services. The men taking part in this study completed a self-administered questionnaire that asked them about whether they had ever smoked cannabis, if they currently smoked it, the number of joints they smoked a week, whether they ever quit and for how many years, age of starting to smoke it, the last time they smoked cannabis and the total duration of cannabis smoking

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