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One of the largest income sources of Indonesia, the kretek industry comprises 500 large and small manufacturers employing a total of around 10 million people

The 2015 tobacco ad regulation states that modern retailers and malls caught putting up tobacco advertisement may be subject to an IDR50 million (US$3,354) fine and risk having their business permits pulled

Epicanthal folds were also prominent [Figure 1a]

Alterations in the composition of the gut microbiome, a condition known as gut dysbiosis, have been strongly associated with a range of diseases, including inflammatory bowel disease (IBD), metabolic syndrome, and various cancers