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Expanded surface area has been reported among individuals at familial high-risk of schizophrenia [63, 64] and is hypothesized to reflect aberrant processes in cell migration early in development (pre/perinatal) or later normative processes to reduce surface area (i.e., synaptic pruning), however, longitudinal research is needed to better elucidate the role of surface area in the pathological process of psychosis [65]

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So while the percentage of American smokers may be going down, the amount of cigarettes smokers consume is steady