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This effect is obvious for smokers with COPD/emphysema, and there is a negative correlation between miR-125a-5p levels and values for forced expiratory volume in one second (FEV1)/forced vital capacity (FVC)

We estimated the cigarette-equivalents consumed per smoker per day using two data sources, namely, self-reported consumption data from household surveys and supply side country-level tobacco consumption data from the Euromonitor (20022017), the US Department of Agriculture (19602005), and the Food and Agriculture Organization of the UN (19612013)

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