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The following changes require prompt professional evaluation, not home treatment: White patches (leukoplakia) on the gums, tongue, or cheeks, potential precancerous lesions Red patches or mixed red-and-white lesions (erythroplakia) , carry high malignant transformation risk Sores or ulcers that do not heal within two weeks Unexplained lumps, swellings, or areas of numbness in the mouth, jaw, or neck Sudden changes in bite or appliance fit Oral cancer risk is significantly elevated in tobacco and e-cigarette users

They cater to smokers who prefer a no-frills smoking experience

Dimensions: 5133 x 3408 px | 43.5 x 28.9 cm | 17.1 x 11.4 inches | 300dpi Date taken: 30 November 2012 Photographer: simon katzer More information: Old lady with sleep blindfold and cigarette with a holder, colourful retro-look

"Frances Yarborough | The Quiet, Steady Partner Behind Don Knotts"