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The study found that adolescents were more likely than adults to use inhalants (2.7% vs 0.4%), with female adolescents showing higher rates than males (3.2% vs 2.3%)

The partnership of Tunis & Annesely, for example, operated sloops that sailed between Philadelphia and ports as far south as Virginia

This may provide the rationale for the healers declared supremacy of the plant (royal plant), which is in line with ethnographic accounts of tobaccos central role in Amazonian healing (e.g., father of all plants) and in the etymology of the healer-term in indigenous Amazonian languages (e.g., he who eats tobacco), as outlined in the introductory section (Shepard, 1998