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In the trial, 18% of e-cigarette users quit smoking after one year, compared to only 9% of NRT users
10.1046/j.1360-0443.2000.951015056.x
The induction of stemness in lung cancer, associated with e-cigarette use, was mediated through upregulation of a stemness marker SRY (sex determining region Y)-box 2 ( Sox2) , a gene that is highly expressed in stem cells and responsible for self-renewal along with the Yes associated protein 1/ E2F transcription factor 1/Octamer-binding transcription factor 4 ( Yap1 /E2F1/ Oct4) signaling axis [26]
Perhaps the most active company in this field has been Philip Morris, now known as Altria Group, Inc
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