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Wu F, Chen Y, Parvez F, Segers S, Argos M, Islam T, et al

14 This protocol emphasises the use of histological assessment and cessation of risk factors, as well as surgical excision where permissible

some medications can be more effective for some smokers if used over a longer pre-quit and for others, if used over an extended post-quit period We have also shown that some early limits on using stop-smoking medications were over-cautious and that some medications, such as varenicline, can be more effective for some smokers if used over a longer pre-quit and for others, if used over an extended post-quit period and that nicotine replacement treatment can be used safely over long term

Any ulcer lasting longer than 3 weeks requires professional evaluation to rule out malignancy