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Further work is needed to understand patterns and motivations for using heated tobacco products, including whether or not young people are actually using these products as a way to transition entirely off of smoking cigarettes. The study also found that a sizable proportion of people (14 percent) who reported using heated tobacco products said they had not previously used any other tobacco products

Wholesalers are required to obtain a license to sell tobacco products.6 A license is required to sell e-cigarette products.10 Youth access laws Effective December 2019, the United States adopted a law raising the federal minimum age of sale of all tobacco products to 21

A., Vollmer, W

[195] This increase in extracellular glutamate presumably occurs via the amphetamine-induced internalization of EAAT3, a glutamate reuptake transporter in some dopamine and norepinephrine neurons