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Active smokers had significantly lower odds of having ANA than nonsmokers in Period 2, as would be expected if CO is protective, but this evident reduction was weaker (and not significant) in Periods 1 and 3

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However, during the same period, average monthly prices significantly decreased in 39 states for rechargeables, in 31 states for disposables, in 20 states for pre-filled cartridges, and in eight states for e-liquids. The Food and Drug Administration is considering just what, if anything, to do about e-cigarettes and other products