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Phone 111 for an ambulance or go to your nearest accident and emergency (A&E) clinic if these occur Signs of an allergic reaction such as itchy skin, and rash, swollen lips or tongue, problems breathing, like a tight chest or shortness of breath

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Both acute and chronic smoking have been reported to induce LV diastolic impairment in normal subjects [15, 16], an effect that seems to be more evident in type-2 diabetes patients [17]

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