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Nano Micro perforation or other material surface treatment , electrostatic cluster perforation, micro perforator, for cigarette, tipping, filter, packaging, plug wrap, Kraft, cement, pet, powder, sack, bag, fine and other paper, silicon or other coating, certain plastic film, laminate, porosity from 80 up to 2,500 C.U., from 50 down to 4 Gurley, hole sizes from 50 nm up to 100 micron, hole densities from 80-260 h/cm2, zone widths from 2.0-6.0mm, up to 16,000,000 holes per Second, web speeds up to 600 m/min, web widths up to 2,000mm
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COPD is currently the third leading cause of mortality worldwide 2 and is characterized by persistent airflow limitation associated with a heightened chronic inflammatory response in the pulmonary tissue 3