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[5] [6] Distribution and habitat [edit] Species in the family Conidae are found in the tropical and subtropical seas of the world, in four biogeographic regions, including: the Indo-Pacific (with 60% of all species), the Tropical Eastern Pacific, the western Tropical Atlantic, and the eastern Tropical Atlantic, plus 10 species in the warm temperate Agulhas bioregion on the southern coast of South Africa

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High level of nicotine activates the sympathetic nervous system leading to a release of epinephrine, norepinephrine and vasopressin hormones 19