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the third part (Part C) consisted of 11 physical and 8 psychological withdrawal symptoms

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Peripheral Artery Disease (PAD): Smoking contributes to the narrowing and hardening of arteries, restricting blood flow to the limbs

In the 81-page report titled Our Epidemic of Loneliness and Isolation, Dr Vivek Murthy took a closer look at the mortality impact of being socially disconnected, with claims that loneliness is associated with a greater risk of stroke, depression, dementia, anxiety, cardiovascular disease, and premature death